Huixin Xu

MutagenesisForge simulates codon-level mutagenesis and calculates dN/dS ratios under user-defined conditions to test evolutionary hypotheses.

This study shows PCL proteins phase-separate to form PRC2 condensates, regulated by CpG islands disrupting their intramolecular interactions.

The paper analyzes somatic mutations across tissues and individuals using exome sequencing data from GTEx donors, identifying 8,470 variants and providing insights into mutation rates and mechanisms.

SOAPTyping is an open-source tool for HLA class I and II allele typing using Sanger sequencing, addressing the lack of free alternatives to commercial software.