Author

Katie Frenis

Boston Children's HospitalORCID 0000-0003-4103-0882Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

R. Grant RoweiD· 2 shared Alex von KriegsheimiD· 1 shared Andreas DaiberiD· 1 shared Brianna Badalamenti· 1 shared Caroline KubaczkaiD· 1 shared Chen WengiD· 1 shared Cormac T. TayloriD· 1 shared Dahai WangiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCell Biology

R. Grant RoweORCID

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3 papers

Recent·Most cited

Cell BiologybioRxivPreprintApr 1, 2026

Efficient Generation of Functional TCRαβ+ Cytotoxic T Cells from hiPSCs via Small-Molecule Modulation

Caroline Kubaczka, Netra K. Kambli, Roland Windisch…·Thorsten M. Schlaeger

This paper identifies small-molecule modulators that enhance the generation of functional cytotoxic T cells from hiPSCs, increasing CTL production up to 2000-fold.

DOI 10.64898/2026.03.31.715684

humanbulk RNA-seq

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Molecular BiologybioRxivPreprintJan 24, 2025

Path of differentiation defines human macrophage identity

Katie Frenis, Brianna Badalamenti, Ohanez Mamigonian…·R. Grant Rowe

This study identifies two distinct macrophage differentiation pathways in humans, showing how developmental origin influences macrophage function and identifies a method to expand tissue-resident macrophages.

1 citation

humanbulk RNA-seq

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Systems BiologybioRxivPreprintApr 22, 2024

Noise Stress induces Cardiovascular Metabolic Shifts

Jair Gonzalez Marques Júnior, Marin Kuntić, Roopesh Krishnankutty…·Alex von Kriegsheim

This study shows that aircraft noise exposure in mice causes rapid metabolic changes in the heart, resembling those in cardiovascular disease.

DOI 10.1101/2024.04.22.590539

mouseexperimental assay

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