Author

Marc Jacobs

Fraunhofer Institute for Algorithms and Scientific ComputingORCID 0000-0003-4153-3930Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Bioinformatics· 4 Neuroscience· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 4 Approach:statistical model· 4 Research Focus:benchmarking· 3 Research Focus:database / resource· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Assay:GWAS summary statistics· 1

Frequent Co-Authors

Martin Hofmann‐ApitiusiD· 4 shared Alpha Tom KodamulliliD· 3 shared Negin Sadat BabaihaiD· 2 shared Alzheimer’s Disease Neuroimaging Initiative· 1 shared Ana SolodkiniD· 1 shared Andrea ZalianiiD· 1 shared Andreas HorniD· 1 shared Bertrand ThirioniD· 1 shared

Activity by Year

2018-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersBioinformatics

Martin Hofmann‐ApitiusORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

BioinformaticsMachine Learning with ApplicationsPeer-reviewedMar 1, 2026

Leveraging Multimodal Large Language Models to Extract Mechanistic Insights from Biomedical Visuals: A Case Study on COVID-19 and Neurodegenerative Diseases

Elizaveta Popova, Marc Jacobs, Negin Sadat Babaiha, Martin Hofmann‐Apitius

This paper uses GPT-4o to extract mechanistic insights from biomedical images related to COVID-19 and neurodegenerative diseases, revealing both established and novel biological connections.

DOI 10.1016/j.mlwa.2025.100816

humanimaging

𝕏 PostBluesky

NeurosciencebioRxivPreprintJan 26, 2026

An Interactive Brain Atlas of Knowledge

Leon Stefanovski, Konstantin Bülau, Leon Martin…·Petra Ritter

The paper develops TVBase, a platform that projects biomedical knowledge onto a 3D brain atlas to support neuroimaging analysis and hypothesis generation.

DOI 10.64898/2025.12.12.694043

humanspatial transcriptomics

𝕏 PostBluesky

BioinformaticsArtificial Intelligence in the Life SciencesPeer-reviewedJul 28, 2025

Unraveling the Co-Morbidity between COVID-19 and Neurodegenerative Diseases Through Multi-scale Graph Analysis: A Systematic Investigation of Biological Databases and Text Mining

Negin Sadat Babaiha, Stefan Geissler, Vincent Nibart…·Martin Hofmann‐Apitius

3 citations

humanGWAS summary statistics

𝕏 PostBluesky

BioinformaticsbioRxivPreprintSep 23, 2020

The COVID-19 PHARMACOME: A method for the rational selection of drug repurposing candidates from multimodal knowledge harmonization

Bruce T. Schultz, Andrea Zaliani, Christian Ebeling…·Martin Hofmann‐Apitius

The paper presents a drug-target-mechanism graph to identify synergistic drug combinations for SARS-CoV-2 treatment, validated through experimental testing.

2 citations

humanstatistical model

𝕏 PostBluesky

BioinformaticsbioRxivPreprintAug 21, 2018

DocClustering: An implementation of the novel PS-Document Clustering algorithm

Jens Dörpinghaus, Sebastian Schaaf, Marc Jacobs

DocClustering implements a novel PS-Document Clustering algorithm for biomedical literature, offering improved accuracy over conventional methods.

DOI 10.1101/397133

statistical modelmachine learning (classical)

𝕏 PostBluesky