BiochemistryScience AdvancesPeer-reviewed
Structures of vertebrate R2 retrotransposon complexes during target-primed reverse transcription and after second strand nicking
Akanksha Thawani, Anthony Rodríguez-Vargas, Briana Van Treeck…·Kathleen Collins
The paper reports cryo-EM structures of A-clade R2 retrotransposon proteins during key steps of transgene insertion and identifies features contributing to their selectivity and function.