Kathleen Collins

The paper introduces OTTR-CLASH, a method that improves the detection of miRNA-target interactions by using a modified RT and enhanced bioinformatics pipeline.

This study expands the known distribution of R2 retrotransposons across animal taxa, identifies new avian candidates, and reveals lineage-specific structural and functional diversity.

The paper identifies nuclear small regulatory RNAs in multivesicular bodies and shows their trafficking requires ESCRT machinery but not LC3 lipidation.

The paper reports cryo-EM structures of A-clade R2 retrotransposon proteins during key steps of transgene insertion and identifies features contributing to their selectivity and function.

This study shows that gammaherpesvirus infection leads to tRNA cleavage, producing tRNA fragments that are regulated by tRNA splicing factors and essential for viral replication.

This study benchmarks the OTTR protocol for characterizing tRNAs and tRNA fragments in yeast and mouse, showing its accuracy and revealing new insights into sperm small RNA content.

The paper improves the OTTR method for RNA sequencing by reducing bias and increasing precision in capturing RNA sequences from degraded or processed RNAs.

The paper introduces a streamlined ribosome profiling method using P1 nuclease and Ordered Two-Template Relay, improving sensitivity and reducing bias in yeast and human cells.

This study shows that TPP1 isoforms and specific residues regulate telomere length set point in human pluripotent stem cells, with TPP1L compensating for TPP1S loss and affecting telomere stability and elongation.