Author

Peter Lotfy

Broad InstituteORCID 0000-0003-0809-7073Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 3 Research Focus:cell-cell communication· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Approach:statistical model· 3 Research Focus:clustering· 2 Organism:human· 2 Assay:imaging· 2

Frequent Co-Authors

Jose Ordovas-MontanesiD· 3 shared Aja PraganaiD· 2 shared Huixin XuiD· 2 shared Maria K. LehtineniD· 2 shared Alina IsakovaiD· 1 shared Andrew C KwongiD· 1 shared Andrew C. YangiD· 1 shared Anna DongiD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersNeuroscience

Jose Ordovas-MontanesORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A fibroblast-CD8+ T cell circuit drives a Type 1 shift in allergic inflammatory memory

Andrew C Kwong, Isabelle Oliver, Lixin Yang, Peter Lotfy, Jose Ordovas-Montanes

This study identifies a fibroblast-CD8+ T cell circuit that drives a Type 1 immune shift in allergic inflammatory memory through mechanistic and translational analysis in murine and human models.

bioRxiv · Nov 4, 2026 · PreprintImmunology

Multi-modal choroid plexus pathology in aging and Alzheimer's disease

Huixin Xu, Peter Lotfy, Benjamin Englert, Jane Oberhauser, Lillian I.J. Byer, Jasmin Wihlman, Kia Colangelo, Serhat Vahip Okar, Ashley A. Thommana, Henri A. J. Puttonen, Mikko I. Mäyränpää, Jarno Tuimala, Rute M. S. M. Pedrosa, Darshan Kumar, James Haberberger, , Maria K. Lehtinen

This study creates a multi-modal atlas of choroid plexus pathology across aging and Alzheimer's disease, identifying fibrosis, calcification, and macrophage abnormalities as key features.

bioRxiv · Jan 1, 2026 · PreprintNeuroscience

A collaboration between immune cells and the choroid plexus epithelium in brain inflammation

Huixin Xu, Peter Lotfy, Sivan Gelb, Aja Pragana, Christine Hehnly, Frederick B. Shipley, Miriam E. Zawadzki, Jin Cui, Liwen Deng, Milo Taylor, Mya Webb, Hart G.W. Lidov, Mark L. Andermann, Isaac M. Chiu, José Ordovás-Montañés, Maria K. Lehtinen

The paper shows the ChP acts as an immune organ in brain inflammation, with immune cell interactions and epithelial cell specialization regulating the barrier.

bioRxiv · Aug 7, 2023 · PreprintNeuroscience