Author

Aurélie Montagne

InsermORCID 0000-0003-4196-1812Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Anne-Laure IscacheiD· 1 shared Hazyadee Frecia Rodríguez-GutiérreziD· 1 shared Roxana KhazeniD· 1 shared Sabina MülleriD· 1 shared Salvatore ValituttiiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperImmunology

Anne-Laure IscacheORCID

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1 paper

Recent·Most cited

ImmunologybioRxivPreprintOct 16, 2026

Selective granzyme B replenishment dominates the molecular switch for sustained cytotoxicity in effector CD8+ T lymphocytes

Hazyadee Frecia Rodríguez-Gutiérrez, Anne-Laure Iscache, Aurélie Montagne…·Roxana Khazen

This study shows that human CTLs sustain cytotoxicity by selectively replenishing granzyme B through de novo synthesis, maintaining its activity and supporting prolonged killing.

DOI 10.64898/2026.10.09.758067

humanexperimental assay

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