Jürgen J. Heinisch

This study identifies Pfk2p as an ATP-dependent RNA unwinding enzyme that modulates cell cycle progression by promoting translation of mitotic genes.

This study shows Rho5 regulates yeast glucose signaling by affecting carbohydrate metabolism, cell wall, and mitochondrial composition, with a role upstream of Ras2 in cAMP-PKA signaling and inhibiting respiratory capacity.

This study shows that the yeast Rho5 GTPase's oxidative stress response depends on its proper spatiotemporal distribution, mediated by its dimeric GEF's localization and activity.

This study shows that tau and α-synuclein regulate microtubule organization and transport in neuronal dendrites, with tau deficiency increasing dendritic complexity and transport efficiency.

This study shows that serine uptake via Gnp1 is critical for maintaining sphingolipid homeostasis in yeast by linking serine import to sphingolipid biosynthesis.