Author

Jiwei Chen

Shanghai Medical College of Fudan UniversityORCID 0000-0003-4202-816XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:ChIP-seq· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Fei CheniD· 2 shared Aileen Huang· 1 shared Aixia SongiD· 1 shared Bolin Tao· 1 shared Cheng Chu ZengiD· 1 shared Congling XuiD· 1 shared Emmalee W. CookeiD· 1 shared Fulai JiniD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersGenetics

Fei ChenORCID

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2 papers

Recent·Most cited

GeneticsScience AdvancesPeer-reviewedJul 4, 2025

H3K79 methylation and H3K36 tri-methylation synergistically regulate gene expression in pluripotent stem cells

Emmalee W. Cooke, Cheng Chu Zeng, Suza Mohammad Nur…·Kaixiang Cao

This study shows that H3K79 methylation and H3K36 tri-methylation work together to control gene expression and neural cell fate in pluripotent stem cells.

3 citations

mouseexperimental assay

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Molecular BiologybioRxivPreprintFeb 7, 2024

Catalytic-independent functions of INTAC in conferring sensitivity to BET inhibition

Pengyu Fan, Xue-Ying Shang, Aixia Song…·Fei Chen

The paper identifies that BET inhibitor efficacy depends on the INTAC complex's auxiliary module, which interacts with the RACK7/ZMYND8-KDM5C complex to remove H3K4 methylation, thereby restoring sensitivity to BET inhibitors through WDR5 degradation.

2 citations

humanChIP-seq

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