Aixia Song

This study identifies DSS1 as an essential subunit of the INTAC complex, showing its role in stabilizing INTAC and its impact on transcriptional regulation.

The paper identifies that BET inhibitor efficacy depends on the INTAC complex's auxiliary module, which interacts with the RACK7/ZMYND8-KDM5C complex to remove H3K4 methylation, thereby restoring sensitivity to BET inhibitors through WDR5 degradation.

This study shows that H3K4me3 dynamics regulate RNA polymerase II pausing through interactions with the INTAC termination complex and Pol II elongation.

The paper identifies RPAP2 as a gatekeeper that prevents preinitiation complex assembly by blocking Pol II-TFIIF interaction, thereby regulating transcription initiation.

The paper presents a high-quality tung tree genome, identifies oil-related genes, and provides insights into genome evolution and oil biosynthesis mechanisms.