Author
Research Center for Advanced Science and Technology, The University of TokyoORCID 0000-0003-4207-1408Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Soh Ishiguro, Kana Ishida, Rina C. Sakata…·Nozomu Yachie
This paper introduces CloneSelect, a multi-kingdom genetic barcoding system that enables precise isolation of target clones using CRISPR base editing to trigger reporter gene expression.
Daniel Evans-Yamamoto, François D. Rouleau, Piyush Nanda…·Christian R. Landry
BFG-PCA is a high-throughput method for discovering binary protein interactions using DHFR-PCA, showing high sensitivity and specificity across human and yeast protein pairs.
Philippe C. Després, Alexandre K. Dubé, M. Seki…·Christian R. Landry
This study uses base editing to systematically mutate over 17,000 sites across 1,500 genes in yeast, identifying 1,100 sites affecting fitness and providing guidelines for effective gRNA design.