Author

Sophia Durney

University of California, San FranciscoORCID 0000-0003-4217-5741Unclaimed ORCID profile · follow to get notified of new preprints

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrei GogaiD· 1 shared Andrew R. Beardsley· 1 shared Daniel Van de Mark· 1 shared Hani GoodarziiD· 1 shared Harrison WismeriD· 1 shared Mary-Kate HaywardiD· 1 shared Nathaniel P. MeyeriD· 1 shared Rachel M. NakagawaiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Andrei GogaORCID

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintSep 26, 2024

Tumor Cell Spatial Organization Directs EGFR/RAS/RAF Pathway Primary Therapy Resistance through YAP Signaling

Rachel M. Nakagawa, Andrew R. Beardsley, Sophia Durney…·Andrei Goga

This study shows that YAP activation in monolayer cultures causes resistance to EGFR/KRAS/BRAF pathway inhibitors, while spheroids are more sensitive, highlighting differences in culture systems for modeling cancer progression.

DOI 10.1101/2024.09.26.615226

humanbulk RNA-seq

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