Sheri Harari

The paper examines how mutations in the HCoV-229E spike affect receptor binding and serum neutralization, revealing counterbalancing effects on these functions.

This study measures the functional and antigenic effects of ~8,500 F protein mutations in Nipah virus using pseudoviruses, revealing constraints on its structure and neutralization by antibodies.

This paper identifies spike mutations in recent SARS-CoV-2 variants that reduce neutralization by human antibodies and clinically relevant monoclonal antibodies, highlighting key sites and mechanisms affecting antigenicity and function.

The paper analyzes intra-host genetic diversity in SARS-CoV-2 chronic infections, finding low frequency mutations and varying divergence rates among patients.

This study identifies molecular mechanisms of FCoV-23 pathogenicity, including receptor usage and biotype switching, and identifies a cross-reactive antibody for therapeutic development.

AccuNGS detects rare viral variants in clinical samples, revealing differences in within-host genetic diversity among HIV, RSV, and CMV infections.