Olivier Raineteau

This study shows that perinatal hypoxia leads to persistent transcriptional and structural changes in cortical neurons, resulting in altered connectivity and behavioral deficits in adult mice.

The paper develops an automated workflow for whole brain analysis of neuronal activity using c-Fos immunohistochemistry and open-source tools, enabling accurate and unbiased quantification across contexts.

This study compares pre- and post-mortem perfusion methods for tissue fixation, finding differences in axonal structures, mitochondrial morphology, and immunostaining quality.

This paper identifies leucovorin and dyclonine as pro-oligodendrogenic compounds through pharmacogenomic screening and validates their therapeutic potential in mouse models of myelin pathologies.

The paper uses single-cell RNA-sequencing to identify quiescent neural stem cells in the dorsal V-SVZ and shows that TGFbeta/BMP signalling drives their quiescence and blocks glutamatergic neurogenesis.

This paper introduces an X-ray phase-contrast tomography method to map myelin in whole rodent brains without staining, showing it can detect and quantify white-matter injuries in disease models.

The paper examines age-related changes in oligodendrocyte precursor cells (OPCs) in APP/PS1 mice, showing accelerated dystrophy and decay compared to non-transgenic controls.

This study shows that synaptic silencing reduces oligodendrocyte precursor cell density and complexity in adult mouse hippocampus.

This study shows that activating astroglia in the lateral habenula prevents the antidepressant effect of bright light stimulation in a mouse model resistant to antidepressants.

This study identifies postnatally-generated CR+ PG cells in the olfactory bulb that retain immature properties and limited network participation.