Functional genomic analyses highlights a shift in Gpr17-regulated cellular processes in oligodendrocyte progenitor cells (OPC) and underlying myelin dysregulation in the aged forebrain
Andrea Domenico Rivera, Francesca Pieropan, Irene Chacon De La Rocha…·Arthur Morgan Butt
The paper identifies GPR17 as a key regulator of OPC dysfunction in aging and identifies potential therapeutic agents to restore myelination.