Author

Yuichi Furuhata

University of California SystemORCID 0000-0003-4299-4819Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:yeast· 2 Research Focus:protein design· 1 Assay:proteomics· 1

Frequent Co-Authors

Chang C. LiuiD· 2 shared Gordon RixiD· 2 shared James A. Van DeventeriD· 1 shared Patrick J. AlmhjelliD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 5 mutual co-author links

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2 shared papersSynthetic Biology

Chang C. LiuORCID

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2 papers

Recent·Most cited

Synthetic BiologyACS Synthetic BiologyPeer-reviewedJun 25, 2026

Continuous hypermutation and evolution of noncanonical amino acid synthases

Yuichi Furuhata, Gordon Rix, Patrick J. Almhjell, Chang C. Liu

This paper evolves noncanonical amino acid synthases in yeast to produce ncAAs from simple precursors, enabling scalable genetic code expansion.

2 citations

yeastproteomics

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Synthetic BiologyNature CommunicationsPeer-reviewedMay 24, 2025

Directed evolution of aminoacyl-tRNA synthetases through in vivo hypermutation

Yuichi Furuhata, Gordon Rix, James A. Van Deventer, Chang C. Liu

This study presents a strategy using OrthoRep to evolve aminoacyl-tRNA synthetases in yeast, resulting in efficient incorporation of non-canonical amino acids into proteins.

16 citationstop 4%

yeastexperimental assay

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