Edward W. J. Wallace

This study shows that Cryptococcus neoformans lacks a spindle position checkpoint, allowing cytokinesis to proceed without proper chromosome segregation.

The paper identifies that the length of the hydrophobic helix in fungal signal peptides determines secretion routes, with shorter helices using the Sec63 translocon and longer ones using the SRP pathway.

This study identifies SsdA-mRNP localization in Aspergillus nidulans hyphae as dependent on endosomal hitchhiking and NDR kinase signaling, revealing spatial regulation during polarized growth.

The paper shows that mRNAs condense broadly in yeast under stress, independent of length, and new transcripts escape this condensation for selective translation.

This study shows that sub-inhibitory azole exposure enhances Candida glabrata virulence by upregulating yapsin proteases and altering host-pathogen interactions.

This study maps 5' and 3' untranslated regions of Aspergillus fumigatus using experimental methods, revealing new regulatory elements and alternative transcription start and stop sites.

This study shows that budding yeast prefer galactose over palatinose despite faster growth on palatinose, challenging the idea that carbon flux-sensing alone determines carbon source preference.

Choros corrects sequence-based biases in ribosome profiling data to provide more accurate quantification of translation dynamics.

riboviz 2 provides a flexible and robust workflow for analyzing and visualizing Ribo-seq data with improved functionality and usability.

The paper investigates how cis-regulatory elements (CREs) affect gene expression in budding yeast, finding that their effects depend on both promoter and terminator contexts.

The paper evaluates workflow management systems for a bioinformatics project using rapid prototyping and selects Nextflow for its workflow.

The paper shows how inactive pseudonucleases in fungi evolved from active Dis3L2 enzymes, retaining non-nuclease functions across lineages.

The paper shows that start codon context regulates translation in fungi, affecting uORF usage and dual-protein localization.

The paper introduces riboviz, a tool for analyzing and visualizing ribosome profiling datasets, providing both a backend pipeline and a web-based interface for comparison with public datasets.