Author

Chrisostomos Prodromou

University of SussexORCID 0000-0003-4320-1147Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:protein structure· 2 Research Focus:protein structure prediction· 2 Organism:human· 1

Frequent Co-Authors

Andrew McGowniD· 1 shared Elena FrasnettiiD· 1 shared Giorgio ColomboiD· 1 shared Ibolya HorváthiD· 1 shared J. Paul ChappleiD· 1 shared John SpenceriD· 1 shared László Vı́ghiD· 1 shared Laura Perna· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Andrew McGownORCID

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2 papers

Recent·Most cited

Molecular BiologyBiomoleculesPeer-reviewedJun 28, 2023

The Crystal Structure of the Hsp90-LA1011 Complex and the Mechanism by which LA1011 may Improve the Prognosis of Alzheimer's Disease.

Stephen Mark Roe, Zsolt Török, Andrew McGown…·Chrisostomos Prodromou

The paper presents the crystal structure of the Hsp90-LA1011 complex and suggests LA1011 may improve Alzheimer's disease prognosis by disrupting FKBP51 binding to Hsp90.

17 citations

protein structureexperimental assay

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Molecular BiologyFrontiers in Molecular BiosciencesPeer-reviewedJan 13, 2023

AlphaFold predicted structure of the Hsp90-like domains of the neurodegeneration linked protein sacsin reveals key residues for ATPase activity

Laura Perna, Matteo Castelli, Elena Frasnetti…·J. Paul Chapple

The paper uses AlphaFold to predict the structure of sacsin's Hsp90-like domains and identifies key residues for ATPase activity, suggesting sacsin functions as an ATP-driven molecular chaperone.

6 citations

humanprotein structure

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