Author

Felix Luessi

University Medical Center of the Johannes Gutenberg University MainzORCID 0000-0003-4334-4199Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 2 Neuroscience· 2 Genetic & Genomic Medicine· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 6 Research Focus:GWAS / association mapping· 4 Assay:GWAS summary statistics· 4 Approach:statistical model· 4 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Bernhard HemmeriD· 3 shared Christina M. LilliD· 3 shared Frauke ZippiD· 3 shared Till F. M. AndlaueriD· 3 shared Adam SantanielloiD· 2 shared An GorisiD· 2 shared Ashley Harris BeechamiD· 2 shared Bénédicte DuboisiD· 2 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenetics

Bernhard HemmerORCID

Mutual co-authors in cluster

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6 papers

Recent·Most cited

NeurosciencebioRxivPreprintMar 9, 2024

Choroid plexus enlargement in acute neuroinflammation is tightly interrelated to the tyrosine receptor signalling

Felix Luessi, Julia Schiffer, Gabriel González‐Escamilla…·Sergiu Groppa

This study identifies tyrosine receptor signalling as linked to choroid plexus enlargement and CSF dynamics in MS neuroinflammation.

2 citations

humanmouse

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Genetic & Genomic MedicinemedRxivPreprintFeb 8, 2024

Genome-wide association study reveals different T cell distributions in peripheral blood of healthy individuals at high genetic risk of type 1 diabetes and long COVID

Laura Deecke, Jan Homann, David Goldeck…·Christina M. Lill

This paper conducts a GWAS to identify genetic loci associated with immune cell distributions in healthy individuals and links these to type 1 diabetes and long COVID risk.

4 citations

humanGWAS summary statistics

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NeuroscienceCell Communication and SignalingPeer-reviewedOct 6, 2023

Assessment of technical and clinical utility of a bead-based flow cytometry platform for multiparametric phenotyping of CNS-derived extracellular vesicles

Alexandra Brahmer, Carsten Geiß, Andriani Lygeraki…·Eva‐Maria Krämer‐Albers

This study evaluates a bead-based flow cytometry platform for detecting CNS-derived extracellular vesicles and identifying disease-specific markers in clinical samples.

23 citations

humanexperimental assay

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Systems BiologyPLoS Computational BiologyPeer-reviewedFeb 3, 2020

DeepWAS: Multivariate genotype-phenotype associations by directly integrating regulatory information using deep learning

Janine Arloth, Gökçen Eraslan, Till F. M. Andlauer…·Nikola S. Mueller

DeepWAS integrates regulatory effect predictions of variants into GWAS to identify regulatory SNPs associated with diseases and traits.

74 citationstop 2%

humanGWAS summary statistics

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GeneticsSciencePeer-reviewedSep 26, 2019

The Multiple Sclerosis Genomic Map: Role of peripheral immune cells and resident microglia in susceptibility

Nikolaos A. Patsopoulos, Sergio E. Baranzini, Adam Santaniello…·John W. Thorpe

The paper reports a detailed genetic and genomic map of multiple sclerosis, identifying susceptibility genes in peripheral immune cells and brain-resident microglia.

1,490 citationstop 1%

humanGWAS summary statistics

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GeneticsCellPeer-reviewedOct 18, 2018

Low frequency and rare coding variation contributes to multiple sclerosis risk

Mitja Mitrovič, Nikolaos A. Patsopoulos, Ashley Harris Beecham…·Hakon H. Hakonarson

The paper identifies low-frequency coding variants contributing to multiple sclerosis risk using a large case-control study.

173 citationstop 1%

humanGWAS summary statistics

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