Author

Laura Deecke

University of MünsterORCID 0009-0002-9268-2469Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 5 Approach:statistical model· 5 Research Focus:GWAS / association mapping· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Assay:GWAS summary statistics· 2 Assay:DNA methylation· 1

Frequent Co-Authors

Christina M. LilliD· 5 shared Jan HomanniD· 5 shared Lars BertramiD· 5 shared Olena OhleiiD· 5 shared Ilja DemuthiD· 4 shared David GoldeckiD· 3 shared Graham PaweleciD· 3 shared André FrankeiD· 2 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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5 shared papersGenetic & Genomic Medicine

Christina M. LillORCID

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Author profile →

5 papers

Recent·Most cited

Peripheral immune profiles in individuals at genetic risk for amyotrophic lateral sclerosis and Alzheimer's disease

Laura Deecke, Olena Ohlei, David Goldeck, Jan Homann, Sarah Toepfer, Ilja Demuth, Lars Bertram, Graham Pawelec, Christina M. Lill

The paper examines immune cell profiles in individuals with genetic risk for ALS and AD, finding nominally significant associations but no significant associations after FDR correction.

Cells · Feb 10, 2025Peer-reviewedGenetic & Genomic Medicine

Immune cell distributions in the blood of healthy individuals at high genetic risk of Parkinson's disease

Laura Deecke, David Goldeck, Olena Ohlei, Jan Homann, Ilja Demuth, Lars Bertram, Graham Pawelec, Christina M. Lill

The paper examines immune cell distributions in healthy individuals at high genetic risk of Parkinson's disease and finds no significant associations between polygenic risk scores and immune cell subtypes, though some nominally significant associations were observed.

International Journal of Molecular Sciences · Dec 20, 2024Peer-reviewedGenetic & Genomic Medicine

Genome-wide association study reveals different T cell distributions in peripheral blood of healthy individuals at high genetic risk of type 1 diabetes and long COVID

Laura Deecke, Jan Homann, David Goldeck, Felix Luessi, Marijne Vandebergh, Olena Ohlei, Sarah Toepfer, Frauke Zipp, Ilja Demuth, Sarah L. Morgan, Lars Bertram, Graham Pawelec, Christina M. Lill

This paper conducts a GWAS to identify genetic loci associated with immune cell distributions in healthy individuals and links these to type 1 diabetes and long COVID risk.

medRxiv · Feb 8, 2024 · PreprintGenetic & Genomic Medicine

Genome-wide QTL mapping across three tissues highlights several Alzheimer's and Parkinson's disease loci potentially acting via DNA methylation

Olena Ohlei, Yasmine Sommerer, Valerija Dobričić, Jan Homann, Laura Deecke, Marcel Schilling, David Bartrés-faz A, Gabriele Cattaneo, Sandra Düzel, Anders M. Fjell, Ulman Lindenberger, Álvaro Pascual‐Leone, Sanaz Sedghpour Sabet, Cristina Solé‐Padullés, Josep M. Tormos, , Lars Bertram

The paper maps DNA methylation quantitative trait loci (meQTL) in three tissues and uses Mendelian randomization to link DNAm to Alzheimer's and Parkinson's disease risk.

medRxiv · Dec 22, 2023 · PreprintGenetic & Genomic Medicine

Genome-wide association study of Alzheimer's disease brain imaging biomarkers and neuropsychological phenotypes in the EMIF-AD Multimodal Biomarker Discovery dataset

Jan Homann, Tim Osburg, Olena Ohlei, Valerija Dobričić, Laura Deecke, Isabelle Bos, Rik R. Vandenberghe, Silvy Gabel, Philip Scheltens, Charlotte Elisabeth Teunissen, Sebastiaan Engelborghs, Giovanni Battista Frisoni, Olivier J. Blin, Jill C. Richardson, Régis Bordet, , Lars Bertram

This study performs GWAS on quantitative AD biomarkers and cognitive traits, identifying new loci associated with memory performance and cognitive decline.

Frontiers in Aging Neuroscience · Mar 21, 2022Peer-reviewedGenetic & Genomic Medicine