Jan Homann

This study finds that DunedinPACE, an epigenetic clock, most consistently associates with cognitive decline in older adults compared to other DNAm clocks and telomere length.

This study identifies lifestyle, early-life, and genetic factors associated with brain age gaps in individuals with major depressive disorder compared to controls.

The paper examines immune cell profiles in individuals with genetic risk for ALS and AD, finding nominally significant associations but no significant associations after FDR correction.

The paper examines immune cell distributions in healthy individuals at high genetic risk of Parkinson's disease and finds no significant associations between polygenic risk scores and immune cell subtypes, though some nominally significant associations were observed.

The paper develops a multivariate methylation risk score using blood DNA methylation data to predict dementia risk and cognitive impairment in Alzheimer's and Parkinson's disease cohorts.

This paper conducts a GWAS to identify genetic loci associated with immune cell distributions in healthy individuals and links these to type 1 diabetes and long COVID risk.

The paper maps DNA methylation quantitative trait loci (meQTL) in three tissues and uses Mendelian randomization to link DNAm to Alzheimer's and Parkinson's disease risk.

This study performs GWAS on quantitative AD biomarkers and cognitive traits, identifying new loci associated with memory performance and cognitive decline.