Lorenzo Ramos‐Mucci

This study characterizes spontaneous OA in CD1 mice, showing progression from mild to severe disease with multi-tissue pathology, establishing them as a robust model for OA research.

The paper creates a single-cell atlas of the healthy human Achilles tendon, identifying six fibroblast subtypes with distinct spatial distributions and transcriptional profiles.

This study investigates sex-specific effects of Fibrillin-1 mutation on knee joint mineralization and osteoarthritis in TSK mice, finding increased pathology in males compared to females.

This study uses single-nucleus RNA sequencing to analyze early cellular changes in human quadriceps tendons after rupture, identifying key cell types and pathways involved in the injury response.

DeepsmirUD predicts small molecule-mediated regulatory effects on miRNA expression using deep learning, achieving high accuracy and enabling drug repositioning insights.