Author

L. H. Tan

Philadelphia VA Medical CenterORCID 0000-0003-4352-654XUnclaimed ORCID profile · follow to get notified of new preprints

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Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2

Frequent Co-Authors

Clayton J. OtteriD· 2 shared Noam A. CoheniD· 2 shared Susan Reich WeissiD· 2 shared Abhishek AsthanaiD· 1 shared Alejandra FaustoiD· 1 shared Anthony R. FehriD· 1 shared Chengjin YeiD· 1 shared David M. RenneriD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersMicrobiology

Clayton J. OtterORCID

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2 papers

Recent·Most cited

MicrobiologyProceedings of the National Academy of SciencesPeer-reviewedMay 17, 2024

Interferon signaling in the nasal epithelium distinguishes among lethal and common cold respiratory viruses and is critical for viral clearance

Clayton J. Otter, David M. Renner, Alejandra Fausto…·Susan Reich Weiss

The paper examines how interferon signaling in nasal epithelial cells differentiates between common cold and lethal respiratory viruses, showing its role in viral clearance.

33 citationstop 4%

humanbulk RNA-seq

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MicrobiologyProceedings of the National Academy of SciencesPeer-reviewedApr 3, 2024

SARS-CoV-2 nsp15 endoribonuclease antagonizes dsRNA-induced antiviral signaling

Clayton J. Otter, Nicole R. Bracci, Nicholas A. Parenti…·Susan Reich Weiss

This study shows that SARS-CoV-2 nsp15 inhibits dsRNA-induced antiviral signaling, which is necessary for viral replication in nasal epithelial cultures.

59 citationstop 1%

humanbulk RNA-seq

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