Author

Perumal Arumugam Desingu

Indian Institute of Science BangaloreORCID 0000-0003-4395-4472Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Assay:metagenomics· 1 Assay:proteomics· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Amarjeet Shrama· 2 shared Ankit Kumar Tamta· 2 shared Nagalingam Ravi SundaresaniD· 2 shared Sukanya RaghuiD· 2 shared Venketsubbu RamasubbuiD· 2 shared Aastha Munjal· 1 shared Amit SinghiD· 1 shared Anurag Nagaraja SharmaiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersPathology

Amarjeet Shrama

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2 papers

Recent·Most cited

PathologybioRxivPreprintOct 22, 2025

SIRT2 attenuates stress-induced skeletal muscle atrophy by inhibiting glucocorticoid receptor signaling

Ankit Kumar Tamta, Bhoomika Shivanaiah, Arathi Bangalore Prabhashankar…·Nagalingam Ravi Sundaresan

This study identifies SIRT2 as a regulator of stress-induced skeletal muscle atrophy by inhibiting glucocorticoid receptor signaling, showing protective effects in mice.

DOI 10.1101/2025.10.22.683887

mouseexperimental assay

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MicrobiologybioRxivPreprintMar 24, 2025

SIRT2 protects against Japanese encephalitis virus infection in mice

Perumal Arumugam Desingu, Lavanya Dindi, Krishnega Murugasamy…·Nagalingam Ravi Sundaresan

This study shows SIRT2 reduces JEV infection in mice by inhibiting NF-κB and enhancing autophagy, improving survival and reducing viral load.

DOI 10.1101/2025.03.24.645101

mouseproteomics

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