Thomas Marissal

This study shows that Htr3a receptors are essential for normal fear response attenuation by regulating oscillatory dynamics and synchronization in the corticolimbic network.

This study investigates the role of Dlx-expressing interneurons in TLE, finding they are largely spared but show reduced activity, and that enhancing their activity can improve cognitive function.

This study demonstrates that gene therapy targeting GluK2 reduces seizures in TLE models and patient-derived slices.

A mouse model with impaired mitochondrial pyruvate import shows neuronal hyperexcitability and seizures despite reduced oxidative phosphorylation.

The paper rescues network dynamics and behaviour in a mouse model of schizophrenia by restoring parvalbumin interneuron excitability.