Alan Carleton

The paper finds that nose-to-ground distance correlates with the number of functional odorant receptor genes in mammals, suggesting olfactory environment complexity drives OR repertoire evolution.

This study creates a spatial single-cell atlas of the claustro-insular region in mice, revealing distinct neuronal subtypes and identifying Nr4a2 as a key regulator of neuronal identity and excitability.

This study investigates the role of the claustrum in working memory by analyzing neuronal activity in mice during memory tasks and finds that claustrum inhibition impairs memory performance.

The paper develops genetic tools to specifically target claustrum neurons in mice, enabling more precise functional studies.

The paper investigates the role of the claustrum in coordinating inter-areal cortical activity and its impact on memory consolidation and retrieval.

This study identifies a Superior Colliculus to VTA neural pathway that controls orienting responses to conspecifics by activating specific dopamine neurons.

A mouse model with impaired mitochondrial pyruvate import shows neuronal hyperexcitability and seizures despite reduced oxidative phosphorylation.

The paper investigates how olfactory sensory neurons adapt transcriptionally to GPCR identity and activity, finding that receptor-specific transcriptomic profiles change with odorant exposure.

The paper identifies sustentacular cells in the human olfactory neuroepithelium as expressing ACE2 and TMPRSS2, suggesting they may serve as entry points for SARS-CoV-2.

Claustrum neurons provide direct excitatory input to medial prefrontal cortex pyramidal cells, and inhibiting claustrum neuronal assemblies suppresses prefrontal assembly formation and prevents attentional set-shifting.

This study examines how neuron selectivity in mouse primary somatosensory cortex changes during reversal learning, finding that most neurons exhibit dynamic selectivity influenced by behavioral context.

The paper shows that glomerular odor representations' similarity and activation strength determine the time needed for odor discrimination, independent of sniffing behavior.

The paper rescues network dynamics and behaviour in a mouse model of schizophrenia by restoring parvalbumin interneuron excitability.