Author

Dahong Chen

National Institutes of HealthORCID 0000-0003-4403-6788Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:ATAC-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Organism:Drosophila· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Elissa P. LeiiD· 3 shared Behram Radmanesh· 1 shared Catherine E. McManusiD· 1 shared Leah F. RosiniD· 1 shared Leah H. Matzat· 1 shared Saumya Keremane· 1 shared Silu WangiD· 1 shared Yang CheniD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 12 mutual co-author links

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3 shared papersGenomics

Elissa P. LeiORCID

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3 papers

Recent·Most cited

GenomicsProceedings of the National Academy of SciencesPeer-reviewedFeb 24, 2025

CTCF regulates global chromatin accessibility and transcription during rod photoreceptor development

Dahong Chen, Saumya Keremane, Silu Wang, Elissa P. Lei

The paper shows that CTCF depletion in mouse rod photoreceptors disrupts chromatin accessibility and gene expression, affecting ~20% of the transcriptome and ~41% of genome accessibility.

7 citations

mouseATAC-seq

𝕏 PostBluesky

GeneticsProceedings of the National Academy of SciencesPeer-reviewedMar 3, 2022

Dosage compensation in Bombyx mori is achieved by partial repression of both Z chromosomes in males

Leah F. Rosin, Dahong Chen, Yang Chen, Elissa P. Lei

This paper visualizes dosage compensation in Bombyx mori males by showing both Z chromosomes are partially repressed, supporting convergent evolution with C. elegans.

28 citationstop 3%

experimental assay

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GenomicsNature CommunicationsPeer-reviewedNov 4, 2021

Temporal inhibition of chromatin looping and enhancer accessibility during neuronal remodeling

Dahong Chen, Catherine E. McManus, Behram Radmanesh…·Elissa P. Lei

The paper identifies enhancer regions that increase in looping frequency with the brat promoter in pupal brains after Shep depletion, showing Shep restricts chromatin accessibility of key enhancers during neuronal remodeling.

10 citations

DrosophilaChIP-seq

𝕏 PostBluesky