Elissa P. Lei

The paper discovers a novel chromatin folding structure, compartment S, in the silkworm Bombyx mori using Hi-C, showing unique loop extrusion and contact patterns.

The paper shows that CTCF depletion in mouse rod photoreceptors disrupts chromatin accessibility and gene expression, affecting ~20% of the transcriptome and ~41% of genome accessibility.

This paper visualizes dosage compensation in Bombyx mori males by showing both Z chromosomes are partially repressed, supporting convergent evolution with C. elegans.

The paper identifies enhancer regions that increase in looping frequency with the brat promoter in pupal brains after Shep depletion, showing Shep restricts chromatin accessibility of key enhancers during neuronal remodeling.

The paper uses Oligopaint FISH to study meiotic chromosome pairing and compaction in Bombyx mori, showing robust pairing in both sexes and similarities to C. elegans bivalent formation.

This study identifies M1BP's role in activating transcription at TAD borders and enhancing chromatin insulator activity through its interaction with CP190.

The paper quantifies transposable element landscapes in aging Drosophila and shows RNAi mechanisms buffer TE expansion despite increased TE expression.