Catherine E. McManus

This study optimizes an ex vivo CAR-T cell-mediated cytotoxicity assay using multimodality imaging to improve real-time tracking and throughput.

The paper identifies enhancer regions that increase in looping frequency with the brat promoter in pupal brains after Shep depletion, showing Shep restricts chromatin accessibility of key enhancers during neuronal remodeling.

This paper introduces a method to isolate high-purity germ nuclei from C. elegans for genomic analyses like ChIP-seq and RNA-seq, without requiring specialized strains or conditions.