Author

Andrea Ninni

University of Rome Tor Vergata

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 4 Research Focus:cell type annotation· 3 Research Focus:cell-cell communication· 3 Approach:experimental assay· 3 Organism:mouse· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2

Frequent Co-Authors

Daniele Lettieri‐BarbatoiD· 3 shared Clément CochainiD· 2 shared Fabio Zaccaria· 2 shared Francesca Sciarretta· 2 shared Giuseppe RizzoiD· 2 shared Katia AquilanoiD· 2 shared Lorenzo NeviiD· 2 shared Luca VerteramoiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersPhysiology

Daniele Lettieri‐BarbatoORCID

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4 papers

Recent·Most cited

TREM2 drives accumulation of pro-scarring monocyte-derived macrophages in the infarcted myocardium

Giuseppe Rizzo, Marie Piollet, Tobias Krammer, Ecem T. Sakalli, Alexander Michael Leipold, Julius Gropper, Paul Alayrac, Adrien Tin-Kim-Wang, Manuel Gendre, Thomas A Prohaska, Paula-Anahi Arias-Loza, Ludovica Timperi, Anna Rizakou, Sourish Reddy Bandi, D. Schulz, , Clément Cochain

This study shows TREM2 drives pro-scarring macrophage accumulation in infarcted myocardium, leading to fibrosis and reduced cardiac repair.

bioRxiv · Aug 21, 2026 · PreprintImmunology

Primary Hyperparathyroidism Reveals Limited Adipose Remodeling in Human

Andrea Palermo, Fabio Zaccaria, Andrea Ninni, Anda Mihaela Naciu, SCIARRETTA Francesca, Luca Verteramo, Cecilia Gentile, Virginia Asia Barbetti, Lorenzo Nevi, Gaia Tabacco, Giorgia Conti, Federico Galli, Ciro Menale, Dario Tuccinardi, Filippo Longo, , Daniele Lettieri‐Barbato

This paper investigates the effects of chronic PTH excess in PHPT on adipose tissue in humans and finds no significant thermogenic or energy-dissipating changes, but identifies a selective secretory phenotype.

bioRxiv · Jul 16, 2026 · PreprintPhysiology

Non-canonical TERT function mitigates adipose tissue inflammation in obesity by modulating stem cell-macrophage communication and macrophage states

Laura Braud, Andrea Ninni, Antonio M.A. Miranda, Émilie Baudelet, Julien Vernerey, Marina Villaverde, Francesca Sciarretta, Manuel Bernabe, Léa Girondier, Ilaria Elia, Jesús Gil, Stéphane Audebert, Jean‐Marc Brondello, Christophe Lachaud, Will Scott, , Vincent Géli

This study shows that TERT expression in adipose tissue reduces inflammation and improves metabolism in obesity by altering macrophage states and stem cell-macrophage communication.

bioRxiv · Dec 18, 2025 · PreprintPhysiology

MACanalyzeR: scRNA-seq Analysis Tool Reveals PPARγHI Lipid-Associated Macrophages Facilitate Thermogenic Expansion in BAT

Andrea Ninni, Fabio Zaccaria, Luca Verteramo, Francesca Sciarretta, Loreana Sanches Silveira, José Cesar Rosa Neto, Simone Carotti, Lorenzo Nevi, Paolo Grumati, Satish Patel, Giulia Carrera, Alessandro Sgambato, Donatella Lucchetti, Filomena Colella, Ilenia Severi, , Daniele Lettieri‐Barbato

The paper introduces MACanalyzeR, a scRNA-seq tool, to identify PPARγ-high lipid-associated macrophages in BAT that support thermogenic expansion.

Nature Communications · May 31, 2025Peer-reviewedPhysiology