Narjes Rohani

This study identifies how the polyglutamine tract in the androgen receptor regulates muscle growth and atrophy by altering transcriptional activity and chromatin binding.

The paper identifies an RA-autoregulatory loop in the developing PFC that maintains RA signaling and defines cortical areal identities.

The paper uses spatial transcriptomics to identify brain regions enriched for ASD and schizophrenia genes in mice, finding the thalamus, cortex, and hippocampus as key areas.

The paper uses STARMAPS to analyze single-cell RNA sequencing data and identifies spatial and temporal patterns of ASD-associated gene enrichment in specific brain regions.

The paper identifies transcriptional and epigenomic differences in Brodmann Area 22 in autism, linking them to RFX3-dependent networks and verbal ability.

The paper maps gene expression responses to loss of 1,947 disease-associated genes across the mouse brain using Perturb-seq, revealing cell-type-specific essentiality and transcriptional programs.

This study identifies 5'UTR exons containing uORFs as targets for splice-switching to increase protein translation in haploinsufficient disease genes.

The paper identifies cell-type-specific molecular and regulatory changes in D1 striosome medium spiny neurons and astrocytes in ASD using single-nucleus multiomic profiling in human putamen.

This study identifies learning strategies and preferences for health data science education through interviews with early career researchers.

This study uses AI to analyze learning strategies in a health data science course, identifying four tactics and three engagement levels that correlate with student success.