Author

Wooi Fang Lim

University of OxfordORCID 0000-0002-1238-3040Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Bioengineering· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:bulk RNA-seq· 3 Organism:mouse· 3 Research Focus:drug response / drug discovery· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Assay:CRISPR screen· 1

Frequent Co-Authors

Matthew J. A. WoodiD· 4 shared Carlo RinaldiiD· 3 shared Alfina A. SpecialeiD· 2 shared Antonio Garcia-GuerraiD· 2 shared Samir EL AndaloussiiD· 2 shared Alessandro Fichera· 1 shared Amarjit BhomraiD· 1 shared André GörgensiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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4 shared papersNeuroscience

Matthew J. A. WoodORCID

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4 papers

Recent·Most cited

Molecular BiologybioRxivPreprintSep 30, 2026

The androgen receptor polyglutamine tract sets the transcriptional balance between muscle growth and atrophy

Francis Grafton, Narjes Rohani, Wooi Fang Lim…·Carlo Rinaldi

This study identifies how the polyglutamine tract in the androgen receptor regulates muscle growth and atrophy by altering transcriptional activity and chromatin binding.

DOI 10.64898/2026.09.29.755413

humanbulk RNA-seq

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BioengineeringNucleic Acids ResearchPeer-reviewedJan 8, 2025

Tissue-specific modulation of CRISPR activity by miRNA-sensing guide RNAs

Antonio Garcia-Guerra, Chaitra Sathyaprakash, Olivier G. de Jong…·Carlo Rinaldi

This paper introduces CRISPR MiRAGE, a miRNA-sensing guide RNA system that enables tissue-specific gene editing by modulating CRISPR activity based on miRNA signatures.

15 citations

mouseCRISPR screen

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NeurosciencebioRxivPreprintOct 18, 2022

Type I PRMT inhibitor MS023 promotes SMN2 exon 7 inclusion and synergizes with nusinersen to rescue the phenotype of SMA mice

Anna J. Kordala, Nina Ahlskog, Muhammad Hanifi…·Carlo Rinaldi

1 citation

mousebulk RNA-seq

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NeuroscienceNature CommunicationsPeer-reviewedNov 18, 2021

GAPDH controls extracellular vesicle biogenesis and enhances therapeutic potential of EVs in silencing the Huntingtin gene in mice via siRNA delivery

Ghulam Hassan Dar, Cláudia C. Mendes, Wei‐Li Kuan…·Matthew J. A. Wood

This study shows GAPDH facilitates EV biogenesis and enables efficient siRNA delivery to the brain, reducing huntingtin gene expression in a mouse model.

100 citationstop 3%

mousebulk RNA-seq

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