Author

Alexandar L. Hansen

The Ohio State UniversityORCID 0000-0003-4474-7141Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1

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Aparna UnnikrishnaniD· 1 shared Ehsan AkbariiD· 1 shared Jonathan S. MontgomeryiD· 1 shared Mark P. FosteriD· 1 shared Michael Guy PoirieriD· 1 shared

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2026-2026 · peak 1/yr

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1 shared paperBiophysics

Aparna UnnikrishnanORCID

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1 paper

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BiophysicsbioRxivPreprintOct 18, 2026

Enhanced DNA Scanning and Target Specificity via Motif Sequestration

Jonathan S. Montgomery, Ehsan Akbari, Alexandar L. Hansen…·Mark P. Foster

This study shows how the Cre recombinase uses a sequestered conformation to enhance DNA scanning efficiency and target specificity by modulating its binding affinity and diffusion behavior.

DOI 10.64898/2026.10.12.758470

experimental assay

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