Author

Sarah A. Mosure

Scripps Research InstituteORCID 0000-0003-4477-5396Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Laura A. SoltiD· 2 shared Douglas J. KojetiniD· 1 shared Jinsai ShangiD· 1 shared Jonathan ChuckiD· 1 shared Mohammed AmiriD· 1 shared Paola Munoz‐TelloiD· 1 shared Patrick R. GriffiniD· 1 shared Qun LuiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

Laura A. SoltORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintJan 28, 2026

Negative regulation of TH17-mediated inflammation by the nuclear receptor REV-ERBβ

Sean Campbell, Sarah A. Mosure, Mohammed Amir…·Laura A. Solt

This study shows REV-ERBβ negatively regulates TH17-mediated inflammation in mouse models, acting independently from REV-ERB through distinct mechanisms.

DOI 10.64898/2026.01.26.701826

mousebulk RNA-seq

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Molecular BiologyScience AdvancesPeer-reviewedJan 27, 2021

Structural basis for heme-dependent NCoR binding to the transcriptional repressor REV-ERBβ

Sarah A. Mosure, Timothy S. Strutzenberg, Jinsai Shang…·Douglas J. Kojetin

The paper resolves conflicting findings on heme's role in REV-ERBβ-NCoR binding by showing heme directly enhances their interaction through structural and biochemical analyses.

26 citations

protein structurestatistical model

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