Author

Jeroen Methorst

Leiden UniversityORCID 0000-0003-4507-4882Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:transformer / foundation model· 1

Frequent Co-Authors

Alexander KrosiD· 1 shared Dennis AschmanniD· 1 shared Herre Jelger RisseladaiD· 1 shared Jan MünchiD· 1 shared Maria HoernkeiD· 1 shared Maximilian KrebsiD· 1 shared Niek van HilteniD· 1 shared Pascal von MaltitziD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperBiophysics

Alexander KrosORCID

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1 paper

Recent·Most cited

BiophysicsbioRxivPreprintApr 22, 2026

A narrow thermodynamic design window governs selective membrane permeabilization and antiviral activity of amphipathic peptides

Niek van Hilten, Pascal von Maltitz, Dennis Aschmann…·Herre Jelger Risselada

The paper identifies a narrow thermodynamic design window for amphipathic peptides to selectively permeabilize viral membranes while sparing host cells, using a physics-driven generative workflow.

DOI 10.64898/2026.04.20.719566

deep learningtransformer / foundation model

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