Author

Pascal von Maltitz

Universität UlmORCID 0000-0003-0533-6999Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Jan MünchiD· 3 shared Dan AlbersiD· 2 shared Elsa Sánchez‐GarcíaiD· 2 shared Frank KirchhoffiD· 2 shared Yasser Almeida‐HernándeziD· 2 shared Alexander KrosiD· 1 shared Andy ChevignéiD· 1 shared Annelies StevaertiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersBiophysics

Jan MünchORCID

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3 papers

Recent·Most cited

BiophysicsbioRxivPreprintApr 22, 2026

A narrow thermodynamic design window governs selective membrane permeabilization and antiviral activity of amphipathic peptides

Niek van Hilten, Pascal von Maltitz, Dennis Aschmann…·Herre Jelger Risselada

The paper identifies a narrow thermodynamic design window for amphipathic peptides to selectively permeabilize viral membranes while sparing host cells, using a physics-driven generative workflow.

DOI 10.64898/2026.04.20.719566

deep learningtransformer / foundation model

𝕏 PostBluesky

Cell BiologyCell Communication and SignalingPeer-reviewedMay 20, 2025

GPR15LG binds CXCR4 and synergistically modulates CXCL12-induced cell signaling and migration

Dan Albers, Sofya Novikova, Julio Vieyto‐Nuñez…·Mirja Harms

This study shows GPR15LG binds CXCR4, enhancing CXCL12-induced signaling and promoting cell migration in immune and cancer cells.

4 citations

humanproteomics

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MicrobiologyAdvanced SciencePeer-reviewedMay 14, 2025

Trypstatin as a Novel TMPRSS2 Inhibitor with Broad-Spectrum 1 Efficacy Against Corona and Influenza Viruses

Jan Lawrenz, Lukas Wettstein, Armando Rodríguez…·Jan Münch

This paper identifies Trypstatin, a Kunitz-type protease inhibitor that inhibits TMPRSS2 and related proteases, showing broad-spectrum antiviral activity against SARS-CoV-2, influenza, and other respiratory viruses.

8 citationstop 3%

humanmouse

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