Author

Denny Liggitt

University of WashingtonORCID 0000-0003-4511-1700Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Aaron B.I. RoseniD· 1 shared Dane A. Grosvenor· 1 shared David J. RawlingsiD· 1 shared Eric J. AllenspachiD· 1 shared Jacob A. Medjo· 1 shared Jane Hoyt BuckneriD· 1 shared Kimberly A. Dill‐McFarlandiD· 1 shared Matthew A. MacQuiveyiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Aaron B.I. RosenORCID

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1 paper

Recent·Most cited

ImmunologyDiabetesPeer-reviewedMar 6, 2025

Reduced function of the adaptor SH2B3 promotes T1D via altered γc cytokine-regulated, T cell intrinsic immune tolerance

Taylor K. Watson, Aaron B.I. Rosen, Travis Drow…·Eric J. Allenspach

This study identifies SH2B3 as a critical regulator of T cell tolerance in T1D, showing that its deficiency enhances cytokine signaling and promotes islet destruction.

4 citations

mousebulk RNA-seq

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