Author

Afshin Dowlati

University Hospitals of ClevelandORCID 0000-0003-4535-6839Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Abbie S. IrelandiD· 1 shared Amy S Joehlin-PriceiD· 1 shared Andrew ElliottiD· 1 shared Anish ThomasiD· 1 shared Ata AbbasiD· 1 shared Benjamin E Hanna· 1 shared Benjamin L. WittiD· 1 shared Charles M. RudiniD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

Abbie S. IrelandORCID

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2 papers

Recent·Most cited

Cancer BiologyNaturePeer-reviewedSep 17, 2025

Basal cell of origin resolves neuroendocrine-tuft lineage plasticity in cancer

Abbie S. Ireland, Daniel A Xie, Sarah B. Hawgood…·Trudy G. Oliver

The paper identifies basal cells as the origin of neuroendocrine-tuft-like tumors in SCLC, revealing lineage plasticity and transcriptional states that mirror human cancer and normal cell injury responses.

48 citationstop 1%

mousebulk RNA-seq

𝕏 PostBluesky

GenomicsMolecular OncologyPeer-reviewedJul 10, 2021

Genomic analyses of high-grade neuroendocrine gynecological malignancies reveal a unique mutational landscape and therapeutic vulnerabilities

Haider Mahdi, Amy S Joehlin-Price, Esther Elishaev…·Ata Abbas

14 citations

humanwhole-exome sequencing

𝕏 PostBluesky