Author

Colin J. Germer

University of California, Los AngelesORCID 0000-0003-4557-4625Unclaimed ORCID profile · follow to get notified of new preprints

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Organism:human· 1

Frequent Co-Authors

Aparna LakkarajuiD· 2 shared Li Xuan TaniD· 2 shared Nilsa La CunzaiD· 2 shared Emma Iorio· 1 shared Fanny M. ElahiiD· 1 shared Gurugirijha RathnasamyiD· 1 shared Kimberly A. ToopsiD· 1 shared Ricardo Espinosa Lima· 1 shared

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2021-2026 · peak 1/yr

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10 top collaborators · 35 mutual co-author links

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2 shared papersNeuroscience

Aparna LakkarajuORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintFeb 22, 2026

Acid sphingomyelinase inhibition restores RPE homeostasis and photoreceptor function in preclinical Stargardt macular degeneration models

Colin J. Germer, Sydney Williams, Valencia Fernandes…·Aparna Lakkaraju

This study shows that inhibiting acid sphingomyelinase (ASM) restores RPE function and photoreceptor health in Stargardt disease models by reducing ceramide accumulation and improving EV biogenesis.

DOI 10.64898/2026.02.20.706984

mouseexperimental assay

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NeuroscienceJCI InsightPeer-reviewedApr 6, 2021

Mitochondria-dependent phase separation of disease-relevant proteins drives pathological features of age-related macular degeneration

Nilsa La Cunza, Li Xuan Tan, Thushara Thamban…·Aparna Lakkaraju

This study identifies mitochondrial stress-mediated protein phase separation as a key pathogenic mechanism in AMD, linking genetic risk factors to RPE dysfunction.

65 citationstop 1%

humanmouse

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