Author

Sydney Williams

Université de Montréal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Neuroscience· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 1

Frequent Co-Authors

Adam G. HendricksiD· 1 shared Ahmad Mahmood· 1 shared Alisa Sandolache· 1 shared Andrew Spira· 1 shared Aparna LakkarajuiD· 1 shared Arinjay BanerjeeiD· 1 shared Arkadeb BhuinyaiD· 1 shared Benjamin Guerin· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperBiophysics

Adam G. HendricksORCID

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3 papers

Recent·Most cited

SARS-CoV-2 maturation driven by a mechano-active nucleocapsid-RNA condensate

Rini Ravindran, Benjamin Guerin, Ahmad Mahmood, Sherry S.W. Leung, Haytham M. Wahba, Pierre Dagenais, Kaushal Baid, Sauhard Shrivastava, Arkadeb Bhuinya, Sydney Williams, Alisa Sandolache, Pascale Legault, James G. Omichinski, Arinjay Banerjee, Paul W. Wiseman, , Stephen W. Michnick

This study shows that SARS-CoV-2 maturation involves N protein-vgRNA condensates that are selectively enveloped by membranes due to RNA-dependent material properties.

bioRxiv · Sep 18, 2026 · PreprintBiophysics

Molecular Determinants Governing the Antitubercular Activity of Griselimycin

Andrew Spira, Sydney Williams, Rachita Dash, Sarah E. Newkirk, Irene Lepori, Yuanhang Caroline Luo, Vaskar Chowhury, Sobika Bhandari, Zichen Liu, Jean A. Chmielewski, M. Sloan Siegrist, Marcos M. Pires

This study investigates the structure-activity relationship of griselimycin, identifying key amino acids and modifications that enhance its antitubercular activity.

bioRxiv · Sep 15, 2026 · PreprintPharmacology & Toxicology

Acid sphingomyelinase inhibition restores RPE homeostasis and photoreceptor function in preclinical Stargardt macular degeneration models

Colin J. Germer, Sydney Williams, Valencia Fernandes, Ricardo Espinosa Lima, Nilsa La Cunza, Li Xuan Tan, Samir Ranjan Panda, Emma Iorio, Fanny M. Elahi, Aparna Lakkaraju

This study shows that inhibiting acid sphingomyelinase (ASM) restores RPE function and photoreceptor health in Stargardt disease models by reducing ceramide accumulation and improving EV biogenesis.

bioRxiv · Feb 22, 2026 · PreprintNeuroscience