Evgeniy A. Ozonov

The paper measures nucleosome occupancy in mouse and human sperm using single-molecule footprinting and finds species-specific differences in residual nucleosome retention.

The paper introduces a statistical model for analyzing single-molecule footprinting data to infer footprint lengths and positions, validated on NOMe-seq datasets from mouse embryonic stem cells.

This study shows that paternal DNA methylation affects nucleosome retention in sperm and H3K4 methylation deposition in early embryos.

This study shows that KDM2A and KDM2B prevent aberrant DNA methylation in mouse oocytes, which is critical for early embryonic development.