NeurosciencebioRxivPreprint
Inhibition of Hsp70 suppresses neuronal hyperexcitability and attenuates seizures by enhancing A-type potassium currents
Fang Hu, Jingheng Zhou, Yanxin Lu…·KeWei Wang
This study shows that inhibiting Hsp70 reduces neuronal hyperexcitability and seizures by boosting A-type potassium currents through the degradation of Kv4-KChIP4a complexes.