Yiping He

This study shows that combining enzalutamide with DRP-104 enhances anti-tumor immunity by reducing Treg cells and improving CD8+ T cell activity in prostate cancer.

DEPICT predicts drug-induced transcriptional responses from gene expression and drug data, outperforming existing methods and enabling drug screening and synergy discovery.

This study investigates how cancer cells adapt to purine shortage stress and identifies vulnerabilities in purine metabolism and microtubules as therapeutic targets.

This paper introduces JGNsc, a method for constructing joint gene networks from scRNA-seq data, and applies it to cancer studies to identify novel findings.