Author

Chengzhe Duan

Northwestern UniversityORCID 0000-0003-4692-1094Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:yeast· 2 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:protein design· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Alexis JacobiD· 1 shared Donna Garvey Brickner· 1 shared Erica M. RosarioiD· 1 shared Guadalupe BravoiD· 1 shared Jake VanBelzeniD· 1 shared Jason H. BrickneriD· 1 shared Kyle KruegeriD· 1 shared Laura L. LackneriD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCell Biology

Alexis JacobORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintMar 25, 2025

The Volume of Mitochondria Inherited Impacts mtDNA Homeostasis in Budding Yeast

Michael W. Ray, WeiTing Chen, Chengzhe Duan…·Laura L. Lackner

The paper shows that the volume of mitochondria inherited by daughter cells in budding yeast affects mtDNA homeostasis, with reduced mitochondrial volume increasing mtDNA loss and requiring copy number upregulation to maintain function.

4 citations

yeastexperimental assay

𝕏 PostBluesky

GenomicsNAR Genomics and BioinformaticsPeer-reviewedJan 5, 2024

ChEC-seq2: an improved Chromatin Endogenous Cleavage sequencing method and bioinformatic analysis pipeline for mapping in vivo protein-DNA interactions

Jake VanBelzen, Chengzhe Duan, Donna Garvey Brickner, Jason H. Brickner

ChEC-seq2 improves DNA cleavage specificity for mapping in vivo protein-DNA interactions by simplifying the protocol and using a new bioinformatic pipeline.

9 citations

yeastChIP-seq

𝕏 PostBluesky