Author

Donna Garvey Brickner

Northwestern University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Cell Biology· 1 Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:yeast· 5 Assay:ChIP-seq· 4 Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:Hi-C· 1

Frequent Co-Authors

Jason H. BrickneriD· 5 shared Jake VanBelzeniD· 2 shared Nikita MarcouiD· 2 shared Agustina D’Urso· 1 shared Alexis JacobiD· 1 shared Bennet G. SakelarisiD· 1 shared Bethany Sump· 1 shared Brian Chait· 1 shared

Activity by Year

2017-2024 · peak 3/yr

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10 top collaborators · 20 mutual co-author links

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5 shared papersGenomics

Jason H. BricknerORCID

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5 papers

Recent·Most cited

Chromatin endogenous cleavage provides a global view of yeast RNA polymerase II transcription kinetics

Jake VanBelzen, Bennet G. Sakelaris, Donna Garvey Brickner, Nikita Marcou, Hermann Riecke, Niall M. Mangan, Jason H. Brickner

The paper compares ChIP-seq and ChEC-seq2 methods to study yeast RNA polymerase II transcription kinetics, finding that ChEC-seq2 better captures promoter and enhancer-bound RNAPII and enables kinetic modeling.

eLife · Nov 28, 2024Peer-reviewedMolecular Biology

ChEC-seq2: an improved Chromatin Endogenous Cleavage sequencing method and bioinformatic analysis pipeline for mapping in vivo protein-DNA interactions

Jake VanBelzen, Chengzhe Duan, Donna Garvey Brickner, Jason H. Brickner

ChEC-seq2 improves DNA cleavage specificity for mapping in vivo protein-DNA interactions by simplifying the protocol and using a new bioinformatic pipeline.

NAR Genomics and Bioinformatics · Jan 5, 2024Peer-reviewedGenomics

Exportin-1 functions as an adaptor for transcription factor-mediated docking of chromatin at the nuclear pore complex.

Tiffany Ge, Donna Garvey Brickner, Kara Zehr, D. Jake VanBelzen, Wenzhu Zhang, Christopher Caffalette, Gavin C. Moeller, Sara Ungerleider, Nikita Marcou, Alexis Jacob, Vu Q. C. Nguyen, Brian Chait, Michael P. Rout, Jason H. Brickner

The paper identifies Crm1 as an adaptor that links transcription factors to chromatin at the nuclear pore complex, facilitating enhancer docking.

Molecular Cell · Jan 1, 2024Peer-reviewedCell Biology

Mitotically heritable, RNA polymerase II-independent H3K4 dimethylation stimulates INO1 transcriptional memory

Bethany Sump, Donna Garvey Brickner, Agustina D’Urso, Seo Hyun Kim, Jason H. Brickner

The paper identifies a mitotically heritable, RNA polymerase II-independent H3K4 dimethylation mechanism that drives transcriptional memory in budding yeast.

eLife · May 17, 2022Peer-reviewedGenetics

The dynamic three-dimensional organization of the diploid yeast genome

Seungsoo Kim, Ivan Liachko, Donna Garvey Brickner, Kate B. Cook, William Stafford Noble, Jason H. Brickner, Jay Shendure, Maitreya J. Dunham

This study examines the 3D genome organization in diploid yeast, finding dynamic homolog proximity and environment-induced gene relocalization.

eLife · May 24, 2017Peer-reviewedGenomics