Author

Jake VanBelzen

Northwestern UniversityORCID 0000-0003-0949-3641Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 2 Organism:yeast· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:protein design· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Donna Garvey Brickner· 2 shared Jason H. BrickneriD· 2 shared Bennet G. SakelarisiD· 1 shared Chengzhe DuaniD· 1 shared Hermann RieckeiD· 1 shared Niall M. ManganiD· 1 shared Nikita MarcouiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

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7 top collaborators · 17 mutual co-author links

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2 shared papersMolecular Biology

Donna Garvey Brickner

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2 papers

Recent·Most cited

Molecular BiologyeLifePeer-reviewedNov 28, 2024

Chromatin endogenous cleavage provides a global view of yeast RNA polymerase II transcription kinetics

Jake VanBelzen, Bennet G. Sakelaris, Donna Garvey Brickner…·Jason H. Brickner

The paper compares ChIP-seq and ChEC-seq2 methods to study yeast RNA polymerase II transcription kinetics, finding that ChEC-seq2 better captures promoter and enhancer-bound RNAPII and enables kinetic modeling.

DOI 10.7554/elife.100764.3

yeastChIP-seq

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GenomicsNAR Genomics and BioinformaticsPeer-reviewedJan 5, 2024

ChEC-seq2: an improved Chromatin Endogenous Cleavage sequencing method and bioinformatic analysis pipeline for mapping in vivo protein-DNA interactions

Jake VanBelzen, Chengzhe Duan, Donna Garvey Brickner, Jason H. Brickner

ChEC-seq2 improves DNA cleavage specificity for mapping in vivo protein-DNA interactions by simplifying the protocol and using a new bioinformatic pipeline.

9 citations

yeastChIP-seq

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