Iszac Burton

This study tracks germinal center responses in rhesus macaques over a year, showing prolonged GCs with declining SHM and ongoing plasma cell production.

This study characterizes the structure and function of antibodies targeting the conserved β-epitope region of PfCSP, showing how they achieve strain-transcending recognition and enhance Fc-mediated immune responses.

This paper demonstrates the feasibility of expressing monoclonal IgG and IgA antibodies in non-human primates using mRNA-LNPs, showing both isotypes retain HIV-neutralizing function and native-like glycosylation.

This study evaluates the dose-dependent effects of the SMNP adjuvant on HIV Env-specific immune responses in non-human primates, showing increased memory T and B cell responses and neutralizing antibodies at higher doses.