Cristian Cañestro

This paper characterizes DO1Cas9, a cold-adapted Cas9 nuclease from the deep ocean, showing improved activity under cold conditions and broader organismal applicability.

This study investigates the molecular response of Oikopleura dioica embryos to underwater noise exposure, finding rapid transcriptomic changes without morphological effects.

This study investigates how Myosin heavy chain gene duplications and losses shaped the evolution of tail muscle diversity in Oikopleura dioica, revealing functional specialization within a minimal musculature.

This study examines the downstream effects of Fgf signaling changes in Oikopleura dioica, showing expanded Fgf receptors and simplified RTK pathways.

CORAL and GAMBA improve genome annotation for compact genomes using long-read RNA-seq, increasing gene count and reducing chimeric predictions in Oikopleura dioica.

This paper investigates how gene loss and duplication in Fgf subfamilies influenced chordate evolution, particularly in appendicularians, revealing evolutionary patterns and functional shifts.

The paper shows extreme genome scrambling in cryptic Oikopleura dioica species, revealing high rates of gene order rearrangements and insights into synteny conservation mechanisms.

The paper tests the developmental toxicity of plastic pellets on invertebrates from multiple phyla, finding concentration-dependent effects on embryonic development and morphogenesis.