Author
Victoria University of WellingtonORCID 0000-0003-4738-6628Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Jeremy G. Owen, Ethan F. Woolly, Hung‐En Lai…·Rory F. Little
DiscERN is a tool for discovering evolutionarily related natural products by analyzing genomes, validated by isolating a new antibiotic.
Vincent V. Nowak, Peng Hou, Jeremy G. Owen
The paper develops a pipeline to analyze microbial communities in marine sponges and identifies biosynthetic novelty in their associated microbes.
Sarah R. Messenger, Edward M. R. McGuinniety, Luke J. Stevenson…·Mark J. Calcott
The paper uses metagenomic domain substitution to generate novel non-ribosomal peptides by screening over 1,000 domains in a pyoverdine NRPS, resulting in 16 distinct products.
Mark J. Calcott, Jeremy G. Owen, David F. Ackerley
The paper demonstrates that substituting adenylation domains in NRPS enzymes can generate novel non-ribosomal peptides, challenging previous assumptions about substrate specificity.