BiochemistrybioRxivPreprint
Synthetic inhibitors of pregnancy-associated plasma protein-A regulate IGF-1 signaling in vitro and in vivo
Anna Kertisová, Shang‐Wu Shih, Nicholas S. Kirk…·Irena Selicharová
This study develops synthetic PAPP-A inhibitors that modulate IGF signaling in vitro and in vivo, showing efficacy comparable to natural inhibitors.
DOI 10.64898/2026.09.30.755852